“The problem is that the infecting bacterium also consumes glucose and that increases the expression of its genes that make it toxic,” said Melanie Blokesch from the Swiss Federal Institute of Technology (EPFL) in Lausanne.Blokesch and Andrea Rinaldo at EPFL correlated data from a recent cholera outbreak in Haiti with the effectiveness of oral rehydration therapy.Blokesch’s lab grew the cholera bacterium with different sugars and starch from potatoes and rice to see how each would affect the cholera toxin genes.The scientists found that both the activity of the genes, as well as the production of the cholera toxin itself were increased when the bacterium was fed with glucose but they were considerably decreased when it was fed with starch from rice. via Post Jagran.
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